Your current location:HOME >sport >Chinese researchers develop targeted nanomedicine for female Alzheimer's patients 正文
TIME:2024-04-20 20:09:14 Source: Internet compilationEdit:sport
TIANJIN, March 13 (Xinhua) -- Chinese researchers have developed a nanomedicine specifically for wom
TIANJIN, March 13 (Xinhua) -- Chinese researchers have developed a nanomedicine specifically for women with Alzheimer's disease.
A research team from Tianjin University's School of Life Sciences and the Tianjin Medical University General Hospital developed the nanomedicine, and the team's work has been published in the Nano Today journal.
Alzheimer's disease is a common neurodegenerative disorder characterized by the progressive degradation of memory and cognitive function. Studies have shown that women are at greater risk of developing Alzheimer's than men, and there is also a notable gender discrepancy in the progression of Alzheimer's, with rates of disease progression and mortality being two to three times higher among women.
Research has indicated that the significant decline in estrogen levels in women after menopause may be the reason women are at greater risk of developing Alzheimer's. Estrogen plays a vital role in safeguarding the female central nervous system, promoting neuronal growth and differentiation, and maintaining brain redox homeostasis by binding to specific receptors. Once women reach menopause, long-term estrogen deficiency induces neurodegeneration and aggravates cognitive decline.
The research team developed a multi-functional nanomedicine utilizing plant-derived estrogen glycyrrhetinic acid for the targeted treatment of postmenopausal female Alzheimer's disease. The nanomedicine is capable of activating neuroprotective signaling pathways mediated by specific estrogen receptors, thereby improving cognitive functions affected by estrogen deficiency.
The research team is now screening more precise nanomedicines for preclinical research.
(Editor:Fu Bo)
Mrs Hinch gives her dog Henry a spa session2024-04-20 20:02
5th China Xizang Tourism and Culture Expo opens in Lhasa2024-04-20 19:59
Mountain and river carnival kicks off in western Beijing2024-04-20 19:42
Complete sponge fossil dating back to 540 mln years found in central China's Hunan2024-04-20 19:41
Crews turn sights to removing debris from ship's deck in Baltimore bridge collapse cleanup2024-04-20 19:33
Eberl ringing alarm bells for Bayern ahead of Arsenal duel2024-04-20 19:01
China's railways handle 16.47M passenger trips on Monday2024-04-20 18:47
Premier League enters its most intriguing title race2024-04-20 18:34
Florida law discriminates against Chinese nationals trying to buy homes, attorneys argue2024-04-20 18:15
Aroma of Chinese Lamian noodles wafts to Belt and Road countries2024-04-20 17:53
Cycling star Evenepoel targets June return from crash ahead of Tour de France and Paris Olympics2024-04-20 20:07
Israel must stop settler attacks on Palestinians, UN office says2024-04-20 18:56
Mom, 28, forced to sell her dream car after forking out $40,000 in INTEREST alone over three years2024-04-20 18:55
UNESCO, Gansu announce partnership2024-04-20 18:25
Swiatek beats Raducanu in Stuttgart quarters. Sabalenka loses to Vondrousova2024-04-20 18:08
Beijing's Yanqing district ready for Labor Day travel rush2024-04-20 17:59
North China's Inner Mongolia launches ancient books database platform2024-04-20 17:57
Tsitsipas advances in Monte2024-04-20 17:51
The iconic fantasy film that catapulted a 172024-04-20 17:37
Maui Fire Department to release after2024-04-20 17:30